Influence of Temperature and pH Changes on Propofol Injection Pain
نویسندگان
چکیده
منابع مشابه
Influence of Temperature and pH Changes on Propofol Injection Pain
Methods: Two hundred patients referred to gastrointestinal or urologic surgery with general anaesthesiology were included in a prospective randomized, double-blind study. After routine monitoring, 5 mL of propofol at room temperature and 5 mL of propofol kept in the fridge was administered within 10 seconds to patients in Group 1 and Group 2, respectively. An investigator assessed pain intensit...
متن کاملPain on injection with propofol
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. CC The use of propofol often results in pain on injection, which is sometimes very distre...
متن کاملPain on Injection of Propofol: Efficacy of Paracetamol and Lidocaine
Background and Objectives: Propofol remains the most common drug for induction of general anaesthesia, although it causes considerable pain on injection. None of the commonly used methods completely attenuate this discomfort. We aimed to investigate the effect of i.v. paracetamol pretreatment on the propofol injection pain. Materials and Methods: A prospective randomized double-blind study was ...
متن کاملPain on injection of propofol: effects of concentration and diluent.
The emulsion formulation of propofol (Diprivan) evokes pain on i.v. injection, although its pH and osmolality are close to those of blood. The pain induced by serial dilutions of propofol in Intralipid and 5% glucose was examined in isolated vein segments and after intracutaneous injection. Propofol evoked pain in a concentration-related manner in six of eight subjects after i.v. perfusion and ...
متن کاملEffect of lignocaine and pH on propofol-induced pain.
Propofol has the disadvantage of pain on injection. A higher partition of propofol in the aqueous phase of the preparation causes a higher incidence of pain on injection while addition of 1% lignocaine to propofol reduces pain. The low concentration of this local anaesthetic and the rapid pain relief observed indicates that mechanisms other than local anaesthesia are involved, that is change in...
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ژورنال
عنوان ژورنال: Turkish Journal of Anesthesia and Reanimation
سال: 2013
ISSN: 1307-7635
DOI: 10.5152/tjar.2013.09